If you search around online, you're bound to come across several "best MyCareer build" lists. They're fantastic but what you should do is just imagine the character you'd like to play 2k22 mt and make your character the same way. Unless you're planning to compete against the top player within The City, you'll be satisfied with whatever character you choose.
Personally, we like playing a tough defense (blocks appear to be overpowered so far this year) and getting our players set up, and hitting occasionally threes when the defense sags off. That might not be for you, so have a play your way around the editors and discover something you enjoy. You'll have much more fun that way.
One of the issues many players have in starting out with MyCareer is that they can't see the floor enough to earn a "B" or better Teammate Rating. Since you start as cheap mt nba 2k22 such an unrated player (unless you decide to spend money in Virtual Currency), you're only going to have a limited number of minutes.